Causes of Dysbiosis

To maintain balance, the normal function of the digestive glands and the acidity of the stomach contents are important. With a decrease or absence of acid in the gastric contents, as well as with the weakening of the digestive glands, a change in the bacterial flora occurs. It may be accompanied by the colonization of the stomach and the nearest small intestine to the stomach by various microorganisms. Also, saprophyte microbes that are in such conditions can cause pain. Contribute to the imbalance of the typical types of microorganisms as well as reduced immunity, vitamin and protein starvation.

May lead to the development of dysbacteriosis intoxication, that is, poisoning of the body, its allergy, hereditary predisposition. The age of the patient, the conditions of his life, the nature of the work, food, past diseases, previous treatment, and the state of immunity of the body matter.

Also, an imbalance in the intestinal microflora can occur under the influence of antibiotics and drugs for the treatment of tuberculosis.

To disturb the intestinal bacterial balance, favorable conditions create damage associated with intestinal poisoning, as well as its sensitization, that is, increased sensitivity.

Microbes spread to the nearest sections of the gastrointestinal tract, which contributes to the development of inflammatory processes of the mucous membrane, impaired motor and excretory functions of the intestine. All this in the sum negatively affects the processes of digestion and causes the clinical manifestations of the disease, that is, the sickness felt by the person. When the intestinal mucosa is inflamed, the intensity of the reconstruction of epithelial cells – integumentary tissues, intestinal walls – decreases. This leads to progressive atrophy of the mucous membrane, reducing the absorption capacity of the intestine. Thus, parietal digestion is disturbed, and incompletely dehydrated products accumulate in the intestinal lumen. There is enteral syndrome – diarrhea, rumbling in the intestines, bloating. In parallel with this, dysfunction of the colon develops.

In addition to local and general exposure to the products of bacterial metabolism and toxins, the ability of microorganisms to promote the activation of digestive enzymes coming from the nearest intestinal sections is lost — they are excreted in large quantities with feces. The consequence of dysbacteriosis is a decrease in the intensity of bacterial production of basic vitamins and their intestinal absorption, the metabolism is disturbed.

Dysbacteriosis leads to a weakening and allergization of the body. And this can cause prolonged inflammatory diseases of the digestive system.

There are several forms of dysbiosis, and this disease is divided into species according to several signs, and in diagnosis it is important to keep in mind how seriously intestinal dysbiosis affects the condition of the whole organism.

When compensated (latent), dysbacteriosis, the body does not respond to the violation of the intestinal bacterial equilibrium.

Subcompensated dysbacteriosis is characterized by the appearance of a local inflammatory process (that is, inflammation of one organ that does not affect the entire body).

Decompensated form – increased development of infection, sometimes even turning into sepsis (blood infection).
According to the severity of dysbiosis is divided into:

  • mild,
  • pronounced
  • pronounced.

By the appearance of microflora disorders, dysbacterioses are secreted:

  • staphylococcal,
  • protective,
  • yeast,
  • associated.

With mild dysbiosis, body temperature is usually normal. The chair is mushy, 2-3 times a day, with mucus. There are abdominal pains, the sigmoid colon may be spasmmed. The chair is restored on the 20-40th day. Intoxication is not observed.

If dysbiosis is moderate in nature, the temperature rises, sometimes it becomes very high, nausea and vomiting occur (more often with staphylococcal dysbacteriosis). Stool is thin, 4–7 times a day, with mucus and pus, abdominal pain, cramped sigmoid colon. Observed body poisoning, however, in a moderate degree. Restoration of the chair – on the 30-50th day. In the analysis of blood detected leukocytosis, stab shift, accelerated erythrocyte sedimentation rate.

Severe dysbacteriosis is characterized by high fever, sometimes chills. The chair is liquid, 10–12 times or more, mucous and bloody, with an admixture of pus. Marked tachycardia, a drop in blood pressure, a serious intoxication poisoning the body. Erythrocyte sedimentation rate, hypoproteinemia and hypocholesterolemia increased. In the analysis of urine protein, red blood cells, white blood cells are detected.

The disease usually lasts from 3 to 9 months, but sometimes more. It can occur with the presence of bacteria in the blood and lead to the development of sepsis, often with staphylococcal dysbacteriosis.

Protein dysbacteriosis is mainly a local intestinal lesion. The course of the underlying disease, complicated by protective intestinal dysbacteriosis, is usually mild or moderate. Sepsis is rare.

More often, generalization occurs with staphylococcal dysbacteriosis.

Caidomiasis dysbacteriosis of the intestine is combined with other clinical manifestations of candidiasis (zaedy, thrush, raspberry tongue).

Especially hard is intestinal dysbiosis, resulting from the association of staphylococcus with other microbes.

local_offerevent_note May 4, 2019

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